Blood Groups: ABO and Rh System

Title
Blood Groups: ABO and Rh System
Description

Blood Groups: ABO and Rh System

Blood group classification is crucial for safe blood transfusions.

ABO System

  • Discovery: Discovered by Karl Landsteiner in 1901 (Nobel Prize 1930).
  • Types: A, B, AB, O — determined by antigens on the red blood cell surface.
  • Universal Status: AB is the universal recipient; O negative (O−) is the universal donor.

Rh Factor

  • Discovery: Discovered in 1940 by Karl Landsteiner and Alexander Wiener.
  • Classification: Rh+ (positive) contains the antigen; Rh− (negative) lacks it.
  • Clinical Significance: Rh incompatibility during pregnancy can cause hemolytic disease of the newborn.

Summary of Types

  • Main types: A+, A−, B+, B−, AB+, AB−, O+, O−.
  • Statistics: O+ is the most common globally; AB− is the rarest.
Category
Medicine
Year of Discovery/Development
1901
Key Person/Organization
Karl Landsteiner

More from Science & Technology